Port Charles prepares for another seismic shift this Monday as General Hospital spoilers for May 5th reveal shocking truths, buried secrets, and emotional reckonings that will leave fans stunned.

The day begins with Carly Spencer stumbling upon a bombshell that threatens to upend everything. Her quiet investigation into suspicious behavior leads her to a disturbing video. The footage, grainy but damning, captures Nina Reeves in a clandestine meeting with Justinda Winters—a meeting that quickly escalates into something darker. As Carly watches, she sees Nina, once a trusted ally, manipulate Justinda into a compromising situation. Moments later, Justinda is lured into Drew Cain’s bedroom, where planted evidence paints him as a drugging predator. The drug in question: ketamine.

Carly’s chest tightens as she replays the video over and over. Nina’s composed expression, Justinda’s trusting demeanor, and the subtle handoff of contraband—all under the dim glow of a single lamp—drive home the reality. This wasn’t just a lapse in judgment. It was a calculated setup. If turned over to the authorities, the tape would almost certainly end Nina’s freedom. But Carly is paralyzed with indecision. Should she pursue justice, or show mercy to someone who once mattered to her?

Meanwhile, Drew is already reeling from the accusation, unaware that he’s been framed. When whispers of the video reach him, he springs into action. With Willow Corinthos at his side, he demands an immediate blood test at GH. The urgency of the situation rings through the hospital’s halls as Dr. Isaiah Ganon collects the sample under the scrutiny of both Drew and Willow. Word spreads quickly: Drew is innocent—and someone is trying to take him down.

But just as Dr. Ganon begins processing the results, Porsche Robinson arrives, wielding influence and determination. Her goal? Delay the release of the results long enough to help Nina mitigate the fallout. What she doesn’t know is that Brad Cooper has been listening in. Desperate to protect himself and nervous about the mounting pressure, Brad leans on Isaiah to think carefully about what revealing the truth might cost.

Isaiah, torn between duty and the pressure from both Porsche and Brad, finds himself at a moral crossroads. The analyzers beep steadily in the background as the ketamine traces appear onscreen. Sweat beads on his brow. Despite their intimidation, his conscience won’t let him bury the truth. With a resolute breath, he prints out the official report and declares, “The results speak for themselves.”

Across town at the Quartermaine mansion, secrets of a different kind are unraveling. Amid the elegant decor and crystal flutes, Brook Lynn Quartermaine drops a personal bombshell. Tearfully, she confesses to her grandmother Tracy that she’s been hiding a teenage pregnancy. Tracy, usually steel and poise, softens at the vulnerability in her granddaughter’s voice and pledges to keep the secret safe. But trust between them remains fragile, and Brook Lynn makes one thing clear: she cannot afford to have this used against her.

Elsewhere, Maxie Jones senses something is off with Lois Cerullo, whose avoidance has finally reached a breaking point. Maxie, pressing gently but firmly, urges her friend to come clean. Lois finally admits that she knows something connected to Brook Lynn’s secret child—but just as she’s about to reveal more, a message from Tracy stops her in her tracks. Lois shuts down immediately, haunted by the realization that Tracy may be orchestrating far more than anyone suspects.

At the Corinthos residence, emotional tension boils over. Lulu Spencer confronts Dante Falconeri, her voice cracking with suppressed emotion. She accuses him of always defending Brook Lynn at her expense, questioning where she stands in his life. Her confession—raw and direct—is one Dante isn’t prepared for: “I love you.” But instead of reciprocating, Dante turns away, unable to face her vulnerability, leaving Lulu shattered and alone in the hallway.

Just as emotions reach a fever pitch among the adults of Port Charles, trouble brews with the younger generation. Danny Morgan and Rocco Falconeri, in a misguided act of rebellion, sneak liquor in the Morgan family barn. Their laughter is short-lived when flashing police lights and sirens descend on the property. Caught and detained, their wild night ends in a holding cell. Dante, still reeling from Lulu’s confrontation, gets the call and races to the station. There, Jason Morgan joins him, the two fathers grimly united as they face the fallout of the boys’ reckless behavior.

Back at the hospital, Carly can’t shake the weight of her discovery. Again, she watches the video, her emotions boiling into resolve. She bursts into Willow’s apartment and forces her to watch the footage. The devastation on Willow’s face is immediate. Moments later, they confront Drew together. As he watches the evidence, realization floods him. He’s been set up, and now he knows by whom.

Fueled by betrayal and a burning need to clear his name, Drew joins Carly and Willow in plotting their next move. They’ll use Dr. Ganon’s lab report to expose Nina and dismantle the conspiracy. But while they steel themselves for battle, back at the hospital lab, the fallout has already begun.

Porsche’s expression darkens as she realizes Isaiah has moved forward with the report. Brad fidgets, knowing the implications. But Isaiah is unwavering. He’s done what’s right, and the truth can’t be hidden anymore.

Soon, detectives link Nina’s name to receipts for ketamine and the symptoms Justinda reported. The net tightens. When officers arrive at Nina’s door, she greets them coldly—but the fear is visible behind her eyes. As the cuffs close around her wrists, Nina’s mind races. This isn’t over—not by a long shot.

Through a pane of glass at the police station, Porsche watches, her composure cracking. She knows the damage is done.

And at the Quartermaine estate, Brook Lynn’s voice trembles as she turns to Tracy one last time. “Will this secret define me forever?” she asks. Tracy, despite her vow, doesn’t answer right away.

As night falls over Port Charles, the quiet tension lingers. Lines have been drawn. Betrayals exposed. And while the storm may seem to pass, everyone knows the real tempest is just beginning.