The latest episode of General Hospital on Wednesday, March 26, 2025, is set to bring high-stakes drama, emotional turmoil, and shocking revelations. At the center of it all is Sonny Corinthos, whose mounting rage threatens to erupt into an irreversible decision. Tensions reach a boiling point when his daughter, Kristina Corinthos-Davis, pushes him to take action against Ava Jerome. However, this request puts Sonny in an impossible situation, torn between his instincts for vengeance and his role as a protector. Ava isn’t just another adversary; she’s the mother of Avery, Sonny’s beloved granddaughter. Taking any action against Ava could cause unimaginable pain for Avery, leaving Sonny struggling with a life-altering choice.
Just as the weight of this decision bears down on him, fate intervenes in an unexpected way. A sudden and severe chest pain grips Sonny, signaling a possible heart attack. The man who has built an empire through sheer resilience now finds himself at the mercy of his own body. With time running out, Sonny does something no one expected—he turns to Ava, the very woman he was poised to confront. In a moment of desperation, he pleads with her to retrieve his heart medication, which he always carries for emergencies. Without hesitation, Ava rushes to help him, putting aside their turbulent history. As Sonny takes the life-saving dose, a silent understanding passes between them, shifting the dynamic of their relationship. A fragile truce emerges, with Ava proving her loyalty in a moment that could have ended in tragedy. Sonny’s health scare forces him to reconsider everything, including his plans for retribution.
Meanwhile, another brewing conflict unfolds within the Quartermaine family. Ned Quartermaine finds himself caught between his daughter Brook Lynn and her mother, Lois Cerullo. While he tries to mediate the rising tensions, he remains unaware of a life-altering secret Lois has been keeping—one that involves Brook Lynn’s past and a hidden pregnancy. This revelation, if exposed, could shake the Quartermaine family to its core. As Lois struggles with whether to tell the truth, Tracy Quartermaine’s relentless pursuit of answers adds to the suspense. Tracy is determined to uncover why Lois is suddenly planning to leave town, sensing that something deeper is at play. The closer Tracy gets to the truth, the more inevitable an explosive confrontation becomes.
Across town, Lucas Jones offers Ava some much-needed advice. He warns her against clinging to the financial entanglements of the Cassadine fortune, reminding her that the pursuit of wealth often comes at a steep emotional cost. His words strike a chord with Ava, making her reconsider her priorities. Will she finally break free from the toxic grasp of the Cassadines, or will her ties to their legacy continue to haunt her?
As these personal battles unfold, another power struggle emerges. Drew Quartermaine makes a daring move that threatens to alter the course of Quartermaine history. He sets his sights on claiming control over the Quartermaine crypt, a move that carries more significance than anyone realizes. However, Emma Drake and Gio Palmieri refuse to let him rewrite history so easily. The two join forces in a high-stakes attempt to protect the family’s legacy, but their efforts come with significant risks. If they fail, the repercussions could be disastrous—not just for the Quartermaines, but for Port Charles as a whole.
Meanwhile, Josslyn Jacks faces a personal setback when she suffers an ankle injury that threatens to derail her training. Her mentor, Valentin Cassadine, steps in to offer guidance, recognizing that this moment of vulnerability could shape Josslyn’s future. A newfound dynamic begins to develop between them, raising questions about whether this mentor-mentee relationship could evolve into something deeper.
Elsewhere, Elizabeth Baldwin finds herself increasingly drawn into Portia Robinson’s hidden struggles. Sensing that Portia is withholding a devastating secret, Liz takes it upon herself to uncover the truth. Her search leads her straight to Ric Lansing, who reveals shocking information—Portia is being blackmailed by none other than Drew Quartermaine. This revelation sends shockwaves through Port Charles, as the extent of Drew’s schemes begins to unravel.
As the episode unfolds, alliances shift, secrets come dangerously close to being exposed, and power struggles reach new heights. With Sonny’s health crisis forcing him to reevaluate his priorities, Ava’s unexpected role in saving his life, and the looming Quartermaine revelations, General Hospital is setting the stage for an unforgettable showdown.