Port Charles is no stranger to jaw-dropping secrets, but nothing could have prepared viewers for the shocking revelation about Kai’s past. In a twist that rewrites history and unearths the darkness of Helena Cassadine’s legacy, it’s discovered that Kai is not just another newcomer — he’s the long-lost child of a woman who perished in a twisted experiment tied to none other than Drew Cain.
This stunning storyline begins to unravel when Sam, investigating Helena’s old files, stumbles across encrypted documents linked to a classified project carried out years ago under Helena’s direct command. The name “Project NEMESIS” resurfaces, tied to dangerous human trials that were quietly buried after Helena’s presumed death. The documents reveal chilling information: several women were unknowingly used as test subjects — including one whose child was secretly taken from her after she died as a result of the experimentation.
As Drew starts to dig into his own murky past, triggered by Sam’s discoveries, he’s overwhelmed by flashes of memories involving a young woman — someone he barely recalls from his time under Helena’s control. With help from Spinelli and Anna, they identify the woman as Cassandra Lyle, a brilliant medical researcher who vanished under mysterious circumstances while working under duress for Helena. The trail leads to a single name: Kai. 
Kai has long struggled with identity issues, unable to piece together where he came from or why he was moved between homes as a child. But now, confronted with the truth that Helena Cassadine had a hand in shaping his tragic beginning, he spirals into emotional turmoil. Even more shocking is the role Drew may have unknowingly played — acting as an enforcer or handler under Helena’s programming while Cassandra was being experimented on.
This revelation sends shockwaves throughout Port Charles. Drew is consumed with guilt, wondering how much of his past actions under Helena’s mind control might have harmed innocent lives. His sense of responsibility toward Kai grows stronger — not only because of his possible involvement in Cassandra’s death, but also because he sees himself in the young man. The trauma, the confusion, the pain — it’s all too familiar.
Meanwhile, the Cassadines aren’t too pleased about this skeleton emerging from the family closet. Valentin, now trying to maintain some semblance of redemption, warns Drew and Sam that there are factions within the Cassadine network who will stop at nothing to prevent any of Helena’s dirty secrets from being fully exposed — especially if it includes evidence that could compromise the family’s power or legacy. Alexis, too, finds herself drawn into the case, as Cassandra was once a law school classmate — a connection she never imagined would resurface in such a harrowing way.
As Kai processes the truth, he becomes determined to uncover every detail of what happened to his mother. He confronts Drew, asking him if he remembers her final moments — but Drew’s memory is fragmented and unreliable. What they do know, however, is that Helena orchestrated Cassandra’s fate with the intention of creating a “genetically superior test subject” — and that Kai may have been the end product of that cruel ambition.
Now, questions linger: What exactly was Helena trying to create? Are there other “offspring” like Kai still out there? And how will Port Charles react to the idea that Helena’s horrific experiments may have left a living legacy walking among them?
This revelation could reshape Drew’s future. Not only is he facing the consequences of his manipulated past, but he’s also standing at a crossroads — does he offer Kai guidance and support, or does he step away and let him forge his own path?
Kai, for his part, may not want anything to do with the people involved in his mother’s demise. But as Helena’s shadows begin to creep back into the present, he may find himself fighting alongside the very people he blames — because the Cassadine curse is far from over.
